Sleep Apnea: Types, Mechanisms, and Clinical Cardiovascular Consequences

Authors: Shahrokh Javaheri, MD, Ferran Barbe, MD, Francisco Campos-Rodriguez, MD, Jerome A. Dempsey, PhD, Rami Khayat, MD, Sogol Javaheri, MD, Atul Malhotra, MD, Miguel A. Martinez-Garcia, MD, Reena Mehra, MD, Allan I. Pack, PhD, Vsevolod Y. Polotsky, MD, Susan Redline, MD, and Virend K. Somers, MD.

Summary:

Review article on the mechanisms of sleep apnea, its links to cardiovascular disease, and the impact of treatment on clinical outcomes.

Key Findings:

OSA is strongly associated with a number of cardiovascular diseases including hypertension, resistant HTN, transient ischemic attack (TIA), stroke, pulmonary hypertension, HF, CHD, AF, myocardial ischemia, myocardial infarction, and sudden death

OSA treated with CPAP after AF intervention had a 44% reduced AF risk (younger, more obese, and male patients benefited the most).

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