Premature ventricular complexes: Assessing burden density in a large national cohort to better define optimal ECG monitoring duration

Authors: Andrew Krumerman, MD, Luigi Di Biase, MD, Edward Gerstenfeld, MD, Timm Dickfeld, MD, Nishant Verma, MD, Leonardo Liberman, MD, Richard Amara, MD, Ardit Kacorri, MD, Lori Crosson, PhD, Alan Wilk, BS, Kevin J. Ferrick, MD.

Summary:

Retrospective study on Zio patches analyzing PVC burden to determine optimal duration of cardiac monitoring.

Key Findings:

Optimal duration of ECG monitoring required to accurately characterize PVC burden is 7 to 10 days and accuracy improved incrementally with continued monitoring up to 14 days.

Misclassification of burden may result in inappropriate therapy.

- 15.6% of patients with <10% PVC burden after 24 hours were reassigned to the 10% – <20% PVC burden group at 14 days.

- 22.4% of patients described as having 10% – <20% PVC burden after 24 hours were reassigned to the <10% PVC burden group at 14 days.

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