Influence of Monitoring Strategy on Assessment of Ablation Success and Postablation Atrial Fibrillation Burden Assessment: Implications for Practice and Clinical Trial Design

Authors: Martin Aguilar, MD, PhD; Laurent Macle, MD; Marc W. Deyell, MD, MSc; Robert Yao, MD; Nathaniel M. Hawkins, MD; Paul Khairy, MD, PhD; Jason G. Andrade, MD.

Summary:

Sub study of CIRCA-DOSE looking at optimal monitoring duration for AF detection post ablation.

Key Findings:

  • Serial long-term (7-14 day) intermittent monitors accumulating at least 28 days of annual monitoring provide estimates of AF burden comparable with ICM.
  • 24-48-hour ECG monitors missing a substantial proportion of recurrences sensitivity, 15.8% - 24.5% , 14 -day ECG monitors 64.6%.

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