Atrial Fibrillation Burden on a 14-Day ECG Monitor: Findings From the GUARD-AF Trial Screening Arm

Authors: Daniel E. Singer, Steven J. Atlas, Alan S. Go, Steven A. Lubitz, David D. McManus, Rowena J. Dolor, Ranee Chatterjee, Michael B. Rothberg, David R. Rushlow, Lori A. Crosson, Ronald S. Aronson, Donna Mills, Michael Patlakh, Dianne Gallup, Emily C. O’Brien, and Renato D. Lopes.

Summary:

Discussion on ECG monitor findings from GUARD-AF in screening arm.

Key Findings:

4.4% AF detection (0.5% persistent, 3.9% paroxysmal).

- Median longest episode 38 min, but on quarter of patients with AF had >= 4.1 hours.

- 0.8% of those with AF had burden >= 10%, 1% had >=5%, and 1.7% had >=2%.

- Median time to AF detection was 140 hours, suggesting 24/48 hour Holters might have missed detection.

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